​The Endocrine Society recently revised their vitamin D guidelines for supplementation and screening, and the revisions sparked an uproar among clinicians (Endocrine Society, 2024, June 03).[1]

​As microscopic colitis (MC) patients, many of us would insist that the gastroenterologists with which we've had appointments devoted precious little attention to many of the symptoms we described. We get the impression that most gastroenterologists still prefer to think of MC as a nuisance disease — just a little diarrhea. And despite all our descriptions of the abdominal pains, joint pains, brain fog, fatigue, and various other symptoms that make life so unpleasant during the day, and prevent us from sleeping at night, if our gastroenterologist acknowledges any of those symptoms at all, he or she typically does so while recommending that we see a good psychiatrist. The disconnect sometimes seems so bad, that we may be surprised that we actually received a correct diagnosis.

When following our gastroenterologist's prescribed cleanout procedure to prepare for a colonoscopy, many of us have discovered that it could be argued that the worst part of the procedure, is convincing ourselves to finish drinking the rest of that prep solution, after we've discovered how nauseating the first few swallows tasted, and we've managed to force about half of it down.

​Apparently, about 1/3 of MC patients are plagued by nausea issues that can range from minor to debilitating, at times. So deciding whether or not to continue drinking the liquid, as the nausea increases, requires a lot of soul-searching, unless we happen to feel invincible (or foolhardy). In some cases, the nausea can be so bad that we're unable to finish, for fear of regurgitating all of it.

​The rapid pace of technological advancement and modernization is outstripping the slow process of human evolution, leading to significant adverse effects on our lives, well-being, and societal stability. This phenomenon, termed evolutionary mismatch, occurs when traits that evolved under previous environmental conditions become maladaptive in the current environment. A recent article published on a phys.org webpage outlines several ways this mismatch appears to be affecting us, and its impact on contemporary issues, including the increasing prevalence of antisocial behavior (Yong, 2024, June 3).[1]​